HyperBiotics Pro-15 Advanced Strength Probiotic Review

This post is sponsored by HyperBiotics and no other compensation was given.

This is my second round of trying out a HyperBiotics brand product. I can say that I am a fan.



I tried the Ultimate Immune System Formula and my review is in a previous post. So far, I think that is it helping me workout hard and prevent any colds derailing my progress. You can read my review here.

But with the binge that I had before I started this weight loss challenge, I am very thankful to be trying out these probiotics.  The information below is from their website.

Hyperbiotics PRO-15 Advanced: Uniquely Formulated to Repopulate Your Gut

15 Broad Spectrum Strains (including Lactobacillus, Bifidobacterium and Streptococcus) to effectively counter the nuking effects of today’s broad spectrum antibiotics.
15 Billion Colony Forming Units per BIO-tract® tablet which is equivalent to 225 Billion CFU (colony forming units) of normal probiotic capsules!††
Kiwi Extract is a Whole Food Superfruit Ingredient, derived entirely from the New Zealand kiwifruit, that helps solve digestion problems and promote colon health while helping your probiotics colonize and take up permanent residence within your intestinal tract.
Naturally Derived Prebiotic included in each tablet to help feed the probiotic for increased potency and effectiveness. Prebiotics are basically fibers that encourage the growth of beneficial bacteria throughout your colon.
Long Shelf Life & No Refrigeration Necessary. With the patented LiveBac® manufacturing process, we offer a guaranteed shelf life of 18 months from the date of manufacture, unlike most probiotics that don’t provide a date of any kind because their organisms die so quickly after being manufactured.
Only Once per Day. That’s it. Because with time-release technology, the full benefits are being delivered deep inside your gut hour by hour.
Relief for your Sensitive Stomach. PRO-15 is released at consistent levels throughout the day and throughout your Gl tract; whereas other probiotics supplement capsules more closely resemble a bomb being dropped in your upper stomach – releasing all organisms at one time, often causing upset such as bloating, gas or diarrhea.
100% Natural. At Hyberbiotics, we don’t believe in additives of any kind.
Vegetarian; Non-GMO and Yeast Free; No Lactose, No Soy, No Iron, No Gluten, No Wheat, No Nuts, No Chemicals, No Preservatives, No Sugar, No Artificial Colors, No Artificial Flavors.

The Science Behind the Superiority

Hyperbiotics PRO-15 is 15x More Effective than Capsules++.
Let us explain…
Gas, bloating, constipation, weakened immune system, malabsorption of nutrients,
candida overgrowth and other health and digestive problems affect many of us on a regular basis.
Probiotics help restore the beneficial gut bacteria that may have been depleted as a result of stress, aging, poor diet, antibiotics, food poisoning, travelers’ diarrhea or infection and promote overall health and well-being.
However, studies show that without protection most probiotics entering the stomach won’t survive to reach optimal sites within the gastrointestinal tract. Powders, liquids, capsules, even cultured dairy products retain only 4% of these sensitive organisms during passage through the stomach’s harsh environment.
The good news: with the patented BIO-tract® protection and time-release technology, we have increased this number to a remarkable 60%.
hyperbiotics vs. capsules

The BIO-tract® Difference

hyperbiotics PRO-15 is 15 times more effective than capsules
When the tablet is moistened by fluids in the stomach, the patented gel matrix creates a protective layer, shielding beneficial organisms from stomach acids and directing them to release later in their journey.
Once inside the gastrointestinal tract, probiotics begin to release at consistent levels from the tablet core, delivering a potent percentage of our living organisms throughout the day and throughout your gut, traveling deep into your intestinal tract where they are needed most.
This is the only controlled-release technology available for probiotics on the market today and is patented in 31 countries (US Patent 8,007,777 and 7,150,623).

The 4 Pillars of Kiwi Extract

Naturally comprised of prebiotics, polyphenols, a kiwi-unique enzyme called actinidin, and insoluble fiber, the four pillars of this simple, yet nutrient dense, ingredient work together to deliver powerful aid to gut healing and gut health.
The prebiotics serve as food and nourishment for probiotics, helping them colonize within your gut while the polyphenols act as powerful antioxidants further helping the probiotics adhere to your intestinal wall.
Actinidin, the natural protease enzyme extracted from organic kiwi fruit, supplements the enzyme activity within your gut, supporting your colon and enabling “business as usual” until your new probiotic colonies are flourishing and producing these necessary enzymes themselves. Meanwhile, with the help of insoluble fiber, the probiotics are are able to move through your system and get to where they need to be.

Top Strains Included in Hyperbiotics PRO-15 Advanced Strength

  • L. fermentum – Identified as highly antimicrobial and antioxidative. Helps inhibit the growth of harmful bacteria, yeast and other pathogens and has demonstrated clinical efficacy within immune health.
  • L. acidophilus – Creates a fortress of good colonies that helps keep unwanted organisms out of your gut. Studies show that L. acidophilus helps to reduce occasional diarrhea and enhances your immune system and may help to reduce cholesterol levels. Studies have shown that those taking L. acidophilus experienced significantly more relief from their gastrointestinal discomfort than did those taking a placebo.
  • L. casei – Along with L. Acidophilus, converts lactose into lactic acid, helping those who are lactose intolerant. Helps to encourage the growth of other beneficial bacteria and has been linked to weight loss.
  • B. longum – Assists in breaking down carbohydrates and fighting free radicals. Provides potent antioxidant support and helps to reduce the effects of seasonal allergens.
  • B. lactis – Helps decrease H. pylori and helps the production of the front line cells in your immune system.
  • L. rhamnosus – The leading defense for travelers. Helps reduce occurrences of traveler’s diarrhea and food poisoning.
  • L. plantarum – Secretes the antioxidant hydrogen peroxide which acts as a weapon to protect your body from disease. Creates a healthy barrier in your colon and helps lower luminal pH, creating an unfavorable environment for the growth of pathogens including molds, yeasts and bacteria.
  • B. infantis – This powerful bacteria occurs naturally in breastmilk as one of nature’s first probiotic gifts. It has been shown to reduce the major symptoms of gastrointestinal disorders, including diarrhea, flatulence, bloating, cramping and constipation. It is particularly popular as a means of combating Irritable Bowel Syndrome (IBS) and has been shown to improve digestion and the body’s ability to absorb and process nutrients.
Pill size

BIO-Tract vs. Enteric Coated and Non-Enteric Coated

Normal, non-enteric coated probiotics offer no protection from a harsh stomach environment, meaning that many do not survive long enough to deliver any benefit. Enteric coated probiotics offer protection from stomach acids with a few drawbacks. First, the organisms are released at one time, in your upper stomach and don’t often make the journey to your small or large intestine. However, the biggest reason for concern is that most enteric coatings are made of a synthetic chemical that the capsule is dipped in. Apart from unwanted added chemicals, the coating contains moisture and air that is detrimental to the probiotic organisms. You see, probiotic powder is ‘hygroscopic’, meaning that it seeks out moisture. The probiotic capsule will start whicking the moisture away from the coating which starts killing the living probiotics inside. Essentially, the enteric coating causes the capsule to self-destruct.
Now you understand the reasons why most capsules that do not require refrigeration also do not have an expiration date. Shelf stability is simply too poor.
Hyperbiotics PRO-15 is 100% naturally derived with a guaranteed shelf life of 18 months.

PRO-15 Vs. Soil Based Organisms (SBOs)

Hyperbiotics PRO-15 strains are lactobacilli and bifidobacteria. They are not soil-based organisms (SBOs), and let us explain why: Lactobacilli and bifidobacteria are resident bacteria in the human GI tract – meaning they colonize and take up residence. SBOs, on the other hand, are transient micro-organisms that establish small colonies for brief periods of time and then die off. We should be exposed to SBOs through interactions with soil and even the vegetables we eat. It is true that the commercialization of food has removed much of this contact from our modern lifestyles.
However, many adults have an even bigger problem: damaged resident flora (lactobacilli and bifidobacteria). This means that they don’t have the proper microbe makeup to interact with soil-based organisms in a healthy and beneficial way. SBOs are spore-forming, they reproduce differently than the beneficial bacteria that are normally part of our flora, and if a person doesn’t have healthy colonies of resident bacteria to keep the soil-based organisms in check, the SBOs can proliferate very rapidly, take over the gut and even become pathogenic. In fact, this poses such a risk that our manufacturing facility considers SBOs to be a contaminant and takes every precaution to ensure they stay out of our facility. Unlike resident probiotics, SBOs are so resistant that they will survive your stomach acids – making them increasingly popular as probiotic supplements.
Hyperbiotics PRO-15 is focused on repopulating the gut of those of us who have damaged our resident bacterial makeup through things like the modern diet high in processed and non plant-based foods, chlorine in our water supply and overexposure to antibiotics (either as medicine or in our food supply).
Once you have strong colonies of resident flora and a healthy GI tract, we absolutely recommend increased exposure to SBO’s… ideally by interacting more with nature (eating freshly grown, organic fruits and vegetables or even gardening, playing in the dirt or just being outside). If a more nature-based lifestyle isn’t an option, SBO supplementation may at that point be a good idea. As a disclaimer, it is our opinion that SBOs should not fall under the category of “probiotics” as it leads to confusion and misinformation.

Bottle label
At Hyperbiotics, our goal is to empower you with knowledge that leads to true health.
Read more about achieving and maintaining a healthy microbiome.

At the time of manufacture.
†† Patented BIO-tract® delivery technology consistently delivers as many as 15 times, or more, the number of live, viable probiotic organisms past simulated stomach acids than (plain/standard) capsules as repeatedly demonstrated through in vitro lab testing.


If interested in learning more about Hyperbiotics Ultimate Immune, you can visit their website, view the product page, Facebook, Instagram, Twitter, YouTube, Pinterest, Vimeo, and Google+. You can also purchase it on Amazon!

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